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The latest blog posts, news, and research from Forever Labs

Dr. Mark Katakowski discusses science that suggests the decline in stems cells plays a role in the physical decline associated with aging.

Watch Mark Katakowski discuss research that suggests the decline in the number and viability of stems cells plays a role in the physical decline associated with aging.

Dr. Mark Katakowski discusses science that suggests the decline in stems cells plays a role in the physical decline associated with aging.

The Latest Blog Posts from Forever Labs

Mark Katakowski and Steven Claustnitzer interviewed on Aaron Watson's Going Deep podcast

Forever Labs President Mark Katakowski & CEO Steven Clausnitzer discuss the benefits and rationale of stem cell storage with Aaron Watson...

Young donor stem cells improve frailty in a clinical trial: What if they had their own younger cells?

In my last blog post, I discussed our plan to transplant our own younger mesenchymal stem cells (MSCs) to our older selves for the purposes of rejuvenation...

Can this startup stop aging? - Forever Labs featured in The Mercury News

Donating Youth to Yourself

Three Questions

DigitalCulture.LA interview with Steven Clausnitzer and Mark Katakowski

Health Maintenance: We can do more

Forever Labs physician Dr. Michael Schenden featured on WXYZ Detroit news

Stroke trial finally published

Why your own cells matter

Do MSCs act exclusively on the immune system in neural injury?

Cellular Senescence in Brief

How young blood might help reverse aging. Yes, really

New Studies Show How Donor Age Affects MSCs’ Disease Fighting Capabilities

What is a stem cell anyway?

What happens to your cells as they age?

Aren't iPS cells the future?

What’s the deal with lifespan?

Welcome, friends!

Steven on The Top Entrepreneur

Client Stories

Mary, a health-conscious 35-year-old nurse, recently shared her Forever Labs stem cell collection experience at Davis & Pyle Plastic Surgery, in Raleigh, North Carolina.

The Latest Blog Posts from Forever Labs

Mark Katakowski and Steven Claustnitzer on Aaron Watson's Going Deep podcast

Young donor stem cells improve frailty in a clinical trial

Can this startup stop aging? - Forever Labs featured in The Mercury News

Donating Youth to Yourself

Three Questions

DigitalCulture.LA with Steven Clausnitzer and Mark Katakowski

Health Maintenance: We can do more

Forever Labs physician Dr. Michael Schenden featured on WXYZ Detroit

Stroke trial finally published

Why your own cells matter

Do MSCs act exclusively on the immune system in neural injury?

Cellular Senescence in Brief

How young blood might help reverse aging. Yes, really

New Studies Show How Donor Age Affects MSCs’ Disease Fighting Capabilities

Steven on The Top Entrepreneur

What is a stem cell anyway?

What happens to your cells as they age?

Aren't iPS cells the future?

What’s the deal with lifespan?

Welcome, friends!

Client Stories

Mary, a health-conscious 35-year-old nurse, recently shared her Forever Labs stem cell collection experience at Davis & Pyle Plastic Surgery, in Raleigh, North Carolina.

 

The Latest Research from Forever Labs

Stem cell transplantation improves aging-related diseases

Transplantation of mesenchymal stem cells from young donors delays aging in mice

Viability and osteogenic potential of cryopreserved human bone marrow-derived mesenchymal cells

Long-term cryopreservation of bone marrow for autologous transplantation

Intravenous transplantation of bone marrow-derived mononuclear cells prevents memory impairment in transgenic mouse models of Alzheimer's disease

Bone marrow-derived mesenchymal stromal cell treatment in patients with severe ischaemic heart failure: a randomized placebo-controlled trial (MSC-HF trial)

Efficacy of mesenchymal stem cells in treating patients with osteoarthritis of the knee: a meta-analysis

Autologous hematopoietic stem cell transplantation in multiple sclerosis: a phase II trial

Cells derived from young bone marrow alleviate renal aging

Donor's age dependent proliferation decrease of human bone marrow mesenchymal stem cells is linked to diminished clonogenicity

Effect on lifespan of high yield non-myeloablating transplantation of bone marrow from young to old mice

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

Forever Labs Blog

When Can I Use My Stem Cells?

I get asked this question a lot. I do not know when you will use your stem cells, or what you will use them for. I will say that you shouldn’t be using your stem cells today, and you shouldn’t be using them tomorrow. However...

Young donor stem cells improve frailty in a clinical trial

In my last blog post, I discussed our plan to transplant our own younger mesenchymal stem cells (MSCs) to our older selves for the purposes of rejuvenation...

Can this startup stop aging? - Forever Labs featured in The Mercury News

"Why it’s cool: Scientists have been chasing the “fountain of youth” for centuries. Now a startup backed by Silicon Valley-based accelerator Y Combinator says it may be within reach of that utopian goal."...

Donating Youth to Yourself

In my previous blog post , I discussed how repairing age-related damage that our bodies accrue can extend our healthspan, and possibly even our lifespan. In this post, I am going to discuss a specific method of health maintenance that we are pursuing at Forever Labs...

Three Questions

As CEO of Forever Labs, I attend as many of our stem cell collections as I can and I talk with many of our clients. The majority of people that are interested in storing their young-adult stem cells with us have the same three questions...

DigitalCulture.LA with Steven Clausnitzer and Mark Katakowski

Brittney Gallagher interviews Steven Clausnitzer, CEO, and Mark Katakowski, President, of Forever Labs about the potentials of storing your adult stem cells...

Health Maintenance: We can do more

The amoeba is a single-cell organism that you might recall from high school biology. Single-cell organisms reproduce asexually. That is, from time to time, if food is plentiful, an amoeba splits in two...

Forever Labs physician Dr. Michael Schenden on WXYZ Detroit

Last week, Dr. Michael Schenden, our first plastic surgeon to offer the Forever Labs procedure in Michigan, was featured on the ABC Detroit affiliate WXYZ...

Stroke trial finally published

The long awaited results of a bone marrow MSC stroke trial were published recently, and the results were quite striking (with caveats that we’ll get to). This topic is near and dear to my heart, as using MSCs for stroke recovery...

Why your own cells matter

Many people have asked us, “Can I use my cells for a family member?” Strictly speaking, you may be able to for some conditions, some of the time. But here, I’d like to discuss why your cells matter to you more than to anyone else...

Do MSCs act exclusively on the immune system in neural injury?

An interesting study came to my attention recently. Last year, a group out of Hannover Medical School in Germany published a report entitled, “ Mesenchymal stem cells do not exert direct beneficial effects on CNS remyelination in the absence of the peripheral immune system.”...

Cellular Senescence in Brief

Forever Labs was founded on the principle that each of us has a valuable reservoir of bone marrow cells, and that as we age this reservoir is depleted, much like an extended drought that has depleted Lake Powell in the Southwest...

How young blood might help reverse aging. Yes, really

In this TED talk , Tony Wyss-Coray studies the impact of aging on the human body and brain. In this eye-opening talk, he shares new research from his Stanford lab and other teams which shows that a solution for some of the less great aspects of old age might actually lie within us all...

New studies show how donor age affects MSCs’ disease fighting capabilities

In the past, I’ve written that there is a strong suggestion that MSCs from older individuals are less likely than those from young ones to fight diseases, but that the evidence—though strong—is mainly circumstantial. However, two very recent studies have shown direct and convincing evidence...

Steven on The Top Entrepreneur

Forever Labs CEO, Steven Clausnitzer, talks stem cells and entrepreneurship on Nathan Latka's podcast, The Top Entrepreneurs in Money, Marketing, Business and Life...

What is a stem cell anyway?

As a biologist, and one who works with bone marrow stem cells in daily life, it’s easy to forget that to the general public, a ‘stem cell’ is not much more than an abstraction, a news-worthy meme that comes light on the details...

What happens to your cells as they age?

The answer is complex and imperfectly understood. In fact, we don't even know why we age. It is taken as a given that we (and every other organism) age, but the fact remains that there isn't an adequate hypothesis about the reason the aging process has evolved to be as it is...

Aren't iPS cells the future?

When talking to friends, colleagues, and others about Forever Labs, those among them with a certain level of knowledge in the biosciences often turn the conversation to iPS cells. Specifically, they want to know why we're trying to do what it is we're trying to do when iPS cells...

What’s the deal with lifespan?

A lot of attention has been paid recently to the life-lengthening capabilities of blood and bone marrow collected from young mice, when injected to older mice. For example, a recent study from Marina Kovina and colleagues in Moscow reported that when they introduced bone marrow from...

Welcome, friends!

This inaugural edition of the Forever Labs blog will attempt to help you make sense of our company, our mission, and why you should continue to check our blog from time to time.

The goals of our organization are simple. We endeavor to put you in the driver seat for your own health...

Mark Katakowski and Steven Clausnitzer on Aaron Watson's Going Deep podcast

Forever Labs President Mark Katakowski & CEO Steven Clausnitzer discuss the benefits and rationale of stem cell storage with Aaron Watson...

Client Stories

Mary, a health-conscious 35-year-old nurse, recently shared her Forever Labs stem cell collection experience at Davis & Pyle Plastic Surgery, in Raleigh, North Carolina.

 

Forever Labs adult stem cell storage client

The Latest in Stem Cell Research

Stem cell transplantation improves aging-related diseases

Aging is a complex process of damage accumulation, and has been viewed as experimentally and medically intractable. The number of patients with age-associated diseases such as type 2 diabetes mellitus (T2DM), osteoporosis, Alzheimer's disease (AD), Parkinson's disease, atherosclerosis, and cancer has increased recently...

Transplantation of mesenchymal stem cells from young donors delays aging in mice

Increasing evidence suggests that the loss of functional stem cells may be important in the aging process. Our experiments were originally aimed at testing the idea that, in the specific case of age-related osteoporosis, declining function of osteogenic precursor cells might be at least partially responsible...

Viability and osteogenic potential of cryopreserved human bone marrow-derived mesenchymal cells

Human bone marrow-derived mesenchymal cells contain mesenchymal stem cells (MSCs), which are well known for their osteo/chondrogenic potential and can be used for bone reconstruction...

Long-term cryopreservation of bone marrow for autologous transplantation

Little is known about the effect of long-term cryopreservation on the viability of hematopoietic stem cells (HSC) or on the success of autologous bone marrow transplantation. Although progenitor cell assays such as culture of CFU-GM after thawing can be predictive of engraftment, the most rigorous assay for the cryosurvival of HSC is engraftment after reinfusion of stem cells...

Intravenous transplantation of bone marrow-derived mononuclear cells prevents memory impairment in transgenic mouse models of Alzheimer's disease

Stem cell transplantation therapy is currently in clinical trials for the treatment of ischemic stroke, and several beneficial aspects have been reported. Similarly, in Alzheimer's disease (AD), stem cell therapy is expected to provide an efficient therapeutic approach...

Bone marrow-derived mesenchymal stromal cell treatment in patients with severe ischaemic heart failure: a randomized placebo-controlled trial (MSC-HF trial)

AIMS: Regenerative treatment with mesenchymal stromal cells (MSCs) has been promising in patients with ischaemic heart failure but needs confirmation in larger randomized trials...

Efficacy of mesenchymal stem cells in treating patients with osteoarthritis of the knee: a meta-analysis

To assess the clinical efficacy and safety of mesenchymal stem cell (MSC) treatment for osteoarthritis of the knee (KOA), a systematic electronic literature search was performed on PubMed, EMBASE and Web of Science. Studies published in English from the earliest record to December 2014 were searched...

Autologous hematopoietic stem cell transplantation in multiple sclerosis: a phase II trial

OBJECTIVE: To assess in multiple sclerosis (MS) the effect of intense immunosuppression followed by autologous hematopoietic stem cells transplantation (AHSCT) vs mitoxantrone (MTX) on disease activity measured by MRI...

Cells derived from young bone marrow alleviate renal aging

Bone marrow-derived stem cells may modulate renal injury, but the effects may depend on the age of the stem cells. Here we investigated whether bone marrow from young mice attenuates renal aging in old mice. We radiated female 12-mo-old 129SvJ mice and reconstituted them with bone marrow cells (BMC) from either 8-wk-old (young-to-old) or 12-mo-old (old-to-old) male mice...

Donor's age dependent proliferation decrease of human bone marrow mesenchymal stem cells is linked to diminished clonogenicity

While mesenchymal stem cells represent an interesting cell source for regenerative medicine, several points have to be investigated to improve their use in clinical, and in particular in the elderly population. This work studied the proliferation capacity of mesenchymal stem cells isolated from human bone marrow in function of donor's age...

Effect on lifespan of high yield non-myeloablating transplantation of bone marrow from young to old mice

Tissue renewal is a well-known phenomenon by which old and dying-off cells of various tissues of the body are replaced by progeny of local or circulating stem cells (SCs). An interesting question is whether donor SCs are capable to prolong the lifespan of an aging organism by tissue renewal...

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

As human lifespan increases, a greater fraction of the population is suffering from age-related cognitive impairments, making it important to elucidate a means to combat the effects of aging. Here we report that exposure of an aged animal to young blood can counteract and reverse pre-existing effects of brain aging at the molecular, structural, functional and cognitive level...

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