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Stem cell transplantation improves aging-related diseases

Aging is a complex process of damage accumulation, and has been viewed as experimentally and medically intractable. The number of patients with age-associated diseases such as type 2 diabetes mellitus (T2DM), osteoporosis, Alzheimer's disease (AD), Parkinson's disease, atherosclerosis, and cancer has increased recently. Aging-related diseases are related to a deficiency of the immune system, which results from an aged thymus and bone marrow cells. Intra bone marrow-bone marrow transplantation (IBM-BMT) is a useful method to treat intractable diseases. This review summarizes findings that IBM-BMT can improve and treat aging-related diseases, including T2DM, osteoporosis and AD, in animal models.

Front Cell Dev Biol. 2014 May 2;2:16. http://www.ncbi.nlm.nih.gov/pubmed/25364723

MORE RESEARCH

TRANSPLANTATION OF MESENCHYMAL STEM CELLS FROM YOUNG DONORS DELAYS AGING IN MICE

Increasing evidence suggests that the loss of functional stem cells may be important in the aging process ...

READ


VIABILITY AND OSTEOGENIC POTENTIAL OF CRYOPRESERVED HUMAN BONE MARROW-DERIVED MESENCHYMAL CELLS

Human bone marrow-derived mesenchymal cells contain mesenchymal stem cells (MSCs), which are well known for their osteo/chondrogenic potential and can be used for bone reconstruction...

READ  

Stem cell transplantation improves aging-related diseases

Aging is a complex process of damage accumulation, and has been viewed as experimentally and medically intractable. The number of patients with age-associated diseases such as type 2 diabetes mellitus (T2DM), osteoporosis, Alzheimer's disease (AD), Parkinson's disease, atherosclerosis, and cancer has increased recently. Aging-related diseases are related to a deficiency of the immune system, which results from an aged thymus and bone marrow cells. Intra bone marrow-bone marrow transplantation (IBM-BMT) is a useful method to treat intractable diseases. This review summarizes findings that IBM-BMT can improve and treat aging-related diseases, including T2DM, osteoporosis and AD, in animal models.

Front Cell Dev Biol. 2014 May 2;2:16. http://www.ncbi.nlm.nih.gov/pubmed/25364723

MORE RESEARCH

TRANSPLANTATION OF MESENCHYMAL STEM CELLS FROM YOUNG DONORS DELAYS AGING IN MICE

Increasing evidence suggests that the loss of functional stem cells may be important in the aging process ...

READ


VIABILITY AND OSTEOGENIC POTENTIAL OF CRYOPRESERVED HUMAN BONE MARROW-DERIVED MESENCHYMAL CELLS

Human bone marrow-derived mesenchymal cells contain mesenchymal stem cells (MSCs), which are well known for their osteo/chondrogenic potential and can be used for bone reconstruction...

READ